Post-Doctoral Fellow

Centre universitaire de santé McGill - Montréal, QC (il y a 30+ jours)

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Job Description
RESEARCH INSTITUTE OF THE MUHC

The Research Institute of the McGill University Health Centre (RI-MUHC) is a world-renowned biomedical and hospital research centre. Located in Montreal, Quebec, the Institute is the research arm of the McGill University Health Centre (MUHC) affiliated with the Faculty of Medicine at McGill University. The RI-MUHC is supported in part by the Fonds de recherche du Québec - Santé (FRQS).

Position summary
We are looking to recruit a postdoctoral fellow to join the laboratory of Dr. Salman Qureshi at the Research Institute of the McGill University Health Centre, a research institute affiliated with the McGill University. The CIHR-funded research project aims to advance knowledge of fungal disease pathogenesis through systematic analysis of cells, molecular pathways, and genes in a clinically relevant mouse model of Cryptococcus neoformans (C. neoformans) infection. The fundamental insights arising from these studies will pave the way for improved management of invasive fungal disease.

Dr. Qureshi’s laboratory has identified two independent chromosomal sub-intervals that significantly reduce fungal burden in the lung and brain, but have distinctly different consequences for the host infected with C. neoformans. Specifically, one of these intervals protects against progressive fungal infection, whereas the other is associated with severe inflammation that models the immune reconstitution inflammatory syndrome (IRIS). IRIS is a life-threatening condition observed during C. neoformans therapy in humans. We are now using highly complementary functional and genetic strategies to identify and characterize the cellular/molecular mechanisms and causal genes that underlie these divergent host responses to C. neoformans infection.

Dr. Qureshi’s laboratory is located in the Centre for Translational Biology (CTB) of the Research Institute of the MUHC (http://rimuhc.ca/-/salman-qureshi-md), a state-of-the-art facility opened in 2015 that provides access to multiple advanced technical platform facilities and an excellent animal facility. The CTB is adjacent to the hospital, providing ready access to patient clinics. Dr. Qureshi’s laboratory is a member of the Translational Research in Respiratory Diseases Program and the Meakins-Christie Laboratories, as well as the McGill University Research Centre on Complex Traits, all of which are collaborative, multidisciplinary research groups.

The postdoctoral fellowship position is for a period of three years. Dr. Qureshi will provide salary for the first year, but will encourage and support applications for internal and external fellowship funding for subsequent years. Salary will be negotiated dependent on experience.

General Duties
  • Design and perform studies, analyze data,
  • Supervise and train students,
  • Collaborate with other lab members and external collaborators,
  • Assist with the preparation of reports, manuscripts and grant applications,
  • Present work at internal, local, national and international meetings.
Website of the organization
https://rimuhc.ca/en

Education / Experience
  • The applicant should have a Ph.D. degree (obtained within the past 1-3 years), and a strong background in immunology and molecular biology,
  • The applicant should also have expertise in flow cytometry, cellular assays, molecular biological methods (e.g., PCR, RT-PCR), and working with mice,
  • Superior written and verbal communication skills.
Please include the following in one (1) PDF document: Cover letter (including a statement of research interests, prior experience in research and how you meet all the above requirements), CV with that includes all publications, contact information for (2) references.
Additional information
Status : Temporary, Full-time
Pay Scale : Based on RI-MUHC post-doctoral stipend scale and commensurate with experience and qualifications
Work Shift : from 9 a.m. to 5 p.m., Mondays to Fridays
Work Site : Centre for Translational Biology, RI-MUHC, Glen site

To learn more about our benefits, please visit https://rimuhc.ca/reasons-to-work-at-the-ri-muhc

THIS IS NOT A HOSPITAL POSITION.

NOTE: The masculine gender has been used for brevity and includes the feminine gender.
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